The goal of SelectSim package is to implement the methodology to infer inter-dependencies between functional alterations in cancer. SelectSim estimates the expected number of mutations in a given gene and a given sample from the mutation frequency of the gene, f(g), and the tumor mutation burden (TMB) of the sample, μ(t). These values can be estimated within specific mutation and tumor subsets, to account for heterogeneous tumor types, tissue specificities, and distinct mutational processes
Installation
- You can install the development version of SelectSim from GitHub with:
# install.packages("devtools")
devtools::install_github("CSOgroup/SelectSim",dependencies = TRUE, build_vignettes = TRUE)- For more details on installation refer to INSTALLATION
Example
Check the the Vignettes folder or visit website
Who do I talk to?
- For any bugs or feature support in using SelectSim, please use the issue tracker.
- For any other question related to SelectSim, please contact Prof Giovanni Ciriello (giovanni.ciriello@unil.ch) or Arvind Iyer (arvind.iyer@unil.ch).